Lipodystrophia centrifugalis abdominalis infantilis in a 4-year-old caucasian girl: association with partial IgA deficiency and autoantibodies

We report the third case of lipodystrophia centrifugalis abdominalis outsid e East Asia. A 4-year-old Caucasian girl developed an area of bluish erythe ma on the left side of the lower abdomen which spread centrifugally to the umbilical and inguinal areas with depression of the skin resulting from the loss of subcutaneous fat, surrounded by an erythematous border. This unusu al skin disease was characterized by clinical and histological examination. Laboratory tests revealed a partial IgA deficiency, antinuclear antibodies and IgG antibodies against gliadin.