EFFICACY OF TOKI-SHIGYAKUKA-GOSYUYU-SYOKYOTO (DANGGUI-SINI-JIA-WUZHUYU-SHENGJIANG-TANG) ON PERIPHERAL-CIRCULATION IN AUTONOMIC DISORDERS

To investigate the improvement in peripheral circulation in autonomic disorders, we monitored skin temperature in the tails of rats by therm ography before and after the oral administration of boiled water extra ct of Toki-shigyakuka-gosyuyu-syokyo-to (TSGS-to). Oral administration of this extract elevated the temperature, calculated as the calories of radiant heat in the rat tail 5-10 min after uptake. The temperature elevation remained stable for more than 20 min. Calories were signifi cantly reduced 60 min after uptake and almost returned to initial valu es 90 min later. Some of the constituent herbs, especially Angelicae r adix, Cinnamomi cortex, Evodiae fructus, and Zingiberis rhizoma, appea red to be active in relieving hypothermia.