Expression of functional immunomodulatory and anti-inflammatory factors inhuman milk

Citation
Rp. Garofalo et As. Goldman, Expression of functional immunomodulatory and anti-inflammatory factors inhuman milk, CLIN PERIN, 26(2), 1999, pp. 361
Citations number
115
Categorie Soggetti
Reproductive Medicine
Journal title
CLINICS IN PERINATOLOGY
ISSN journal
00955108 → ACNP
Volume
26
Issue
2
Year of publication
1999
Database
ISI
SICI code
0095-5108(199906)26:2<361:EOFIAA>2.0.ZU;2-0
Abstract
Human milk contains a wealth of components that can directly modulate the i mmunological development as well as the antimicrobial defenses of the recip ient infant without inducing unwanted inflammatory responses. The presence of these immunomodulatory and anti-inflammatory factors in human milk sugge sts a coordinated evolution of the development bf the immune system of the infant and the ability of the mother to produce and secrete immune factors from the mammary gland. This article reviews some of the major findings rel ated to the presence and function of immunomodulatory and anti-inflammatory factors in human milk.