Human milk is beneficial in the management of premature infants. The benefi
cial effects generally relate to improvements in host defenses, digestion,
and absorption of nutrients, gastrointestinal function, neurodevelopment, a
nd maternal psychological well-being. The use of fortified human milk gener
ally provides the premature infant adequate growth, nutrient retention, and
biochemical indices of nutritional status when fed at approximately 180 mL
/kg/day compared with unfortified human milk. Human milk can only support t
he needs of the premature infant if adequate milk volumes are produced. Int
ensive efforts at lactation support are desirable. Therefore, neonatal cent
ers should encourage the feeding of fortified human milk for premature infa
nts along with skin-to-skin contact as a reasonable method to enhance milk
production and promote success with early breastfeeding, while potentially
facilitating the development of an enteromammary response.