Dermatophytic granuloma caused by Microsporum canis in a heart-lung recipient

Citation
Jj. Voisard et al., Dermatophytic granuloma caused by Microsporum canis in a heart-lung recipient, DERMATOLOGY, 198(3), 1999, pp. 317-319
Citations number
15
Categorie Soggetti
Dermatology
Journal title
DERMATOLOGY
ISSN journal
10188665 → ACNP
Volume
198
Issue
3
Year of publication
1999
Pages
317 - 319
Database
ISI
SICI code
1018-8665(1999)198:3<317:DGCBMC>2.0.ZU;2-1
Abstract
We present a case of dermatophytic granuloma caused by Microsporum canis in a heart-lung recipient. This 66-year-old man was seen for erythematous pus tules and papules on the forearm. The diagnosis was suspected after histolo gical examination showing an inflammatory infiltrate in the upper dermis wi th giant cells containing intracytoplasmic fungal elements. Cultures of the skin biopsy confirmed the diagnosis identifying M. canis. Our case emphasi zes the possibility of deep dermatophytic infections in immunocompromised p atients. There are only 4 additional reports of M. canis infection responsi ble for invasion of the dermis in such patients. The follicle involvement p robably explains these dermal lesions due to the progression of the dermato phyte from the hair follicle to the dermis. In our observation topical anti fungal therapy alone was unsuccessful and fluconazole seems to be the treat ment of choice for these M. canis invasive dermal cutaneous infections.