The global phase diagram (GPD) of model binary mixtures of water and n-alka
nols has been determined using the statistical associating fluid theory (SA
FT) equation of state (EOS). Closed regions in the two-dimensional paramete
r space (the strength of the hydrogen bond of alkanol vs. the length of the
alkanol molecule), where azeotropy and closed liquid-liquid immiscibility
loops occur, have been found. When the diagram is transformed to the space
of relative critical temperatures and volumes, no real aqueous mixture of a
lkanol lies in these regions; the disagreement is caused by the choice of p
arameters in this work, (C) 1999 Elsevier Science B.V. All rights reserved.