E. Birnie et al., COST-MINIMIZATION ANALYSIS OF DOMICILIARY ANTENATAL FETAL MONITORING IN HIGH-RISK PREGNANCIES, Obstetrics and gynecology, 89(6), 1997, pp. 925-929
Objective: To compare safety and cost-effectiveness of domiciliary ant
enatal fetal monitoring (cardiotocography and obstetric surveillance)
with in-hospital monitoring in highrisk pregnancies. Methods: From Sep
tember 1992 to June 1994, 150 consecutive women with high-risk pregnan
cies, who would otherwise be monitored in the hospital, entered a rand
omized controlled trial of in-hospital (n = 74) or domiciliary (n = 76
) monitoring. The main outcome measures were neonatal safety (Prechtl
neurologic optimality score, the proportion of non-optimals) and cost-
effectiveness. To test a two-point difference in mean Prechtl scores (
two-tailed alpha = .05, 1-beta = .80), 150 women were needed. Safety a
nd cost-effectiveness were analyzed according to intention to treat. C
onditional on the safety outcomes, a cost-minimization analysis based
on actual resource use was performed. Uncertainty of results was explo
red by sensitivity analyses. Results: Neonatal outcomes were equal. No
cost-shifting between the antenatal and postpartum period occurred. S
ubstituting domiciliary for in-hospital monitoring reduced mean (stand
ard deviation) antenatal costs from $3558 ($2841) to $1521 ($1459) per
woman (P < .001). If costs were varied by the addition of 50%, costs
were still reduced. The magnitude of the reduction was sensitive to th
e costs of hospital care and less sensitive to the costs of domiciliar
y monitoring. Conclusion: Domiciliary monitoring is safe and reduces c
osts by one-half. The technique seems transferable to other settings b
ut local circumstances may sometimes hamper its dissemination. (C) 199
7 by The American College of Obstetricians and Gynecologists.