Hemodynamic abnormalities in sodium monofluoroacetate intoxication

Hypotension is one of the most important predictors of mortality in sodium monofluoroacetate (SMFA) intoxication. This paper reports the hemodynamic r esponse in one fatal and another survival case of SMFA intoxication. Despit e correction of hypovolemia and with inotropic support, the patients remain ed in shock. Hemodynamic observations have provided evidence that shock aft er SMFA intoxication is due to diminished systemic vascular resistance and increased cardiac output. This is the first report in which such an invasiv e hemodynamic investigation has been recorded in a clinical case of SMFA in toxication.