Invasive lesions containing filamentous forms produced by a Candida albicans mutant that is defective in filamentous growth in culture

Authors
Riggle, FJ Andrutis, KA Chen, X Tzipori, SR Kumamoto, CA
Citation
Fj. Riggle et al., Invasive lesions containing filamentous forms produced by a Candida albicans mutant that is defective in filamentous growth in culture, INFEC IMMUN, 67(7), 1999, pp. 3649-3652
Citations number
12
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
67
Issue
7
Year of publication
1999
Pages
3649 - 3652
Database
ISI
SICI code
0019-9567(199907)67:7<3649:ILCFFP>2.0.ZU;2-3
Abstract
A Candida albicans efg1 cph1 double mutant is nonfilamentous under standard laboratory conditions and avirulent in mice. However, this mutant produced filaments in the tongues of immunosuppressed gnotobiotic piglets and when embedded in agar, demonstrating that an Efg1p- and Cph1p-independent pathwa y for promotion of filamentous growth exists.