Chlamydial colonization of multiple mucosae following infection by any mucosal route

Chlamydia trachomatis inoculated by any mucosal route colonized multiple mu rine mucosae and, in most cases, the spleen, liver, and kidneys. Cell-to-ce ll transmission, systemic dissemination, and autoinoculation of infectious fluids may have contributed to chlamydial spread. Intermucosal trafficking of protective T cells cannot be accurately evaluated by using live chlamydi al challenges.