A questionnaire survey was sent to a random sample of the Spanish network o
f National Health System public acute-care hospitals. Of responding institu
tions (representing 25% of Spanish hospital beds), nearly 75% had active su
rveillance programs for the prevention and control of surgical-site infecti
ons (SSIs), but only 20% performed postdischarge surveillance. Overall, per
ioperative antibiotic prophylaxis (PAP) was used in 84% of all surgical pro
cedures. For 77% of procedures, there were written guidelines for the choic
e and use of PAP. Cefazolin was the most commonly used antibiotic (38%). Du
ration of PAP was shorter than 24 hours in 75% of procedures, and only a si
ngle dose was given in 52% of procedures. PAP was commonly used in breast (
52%) and inguinal hernia repair (69%) procedures, as well as in laparoscopi
c abdominal surgery (86%). In summary, the use of PAP in Spanish hospitals
is adequate, but Improvements can be made in the frequency of prolonged PAP
and in the use of broad-spectrum antibiotics. Surveillance systems for SSI
, including postdischarge follow-up, also should be improved (Infect Contro
l Hosp Epidemiol 1999;20:436-439).