Case of gonadoblastoma in a 9-year-old boy without physical abnormalities

Background: A 9-year-old boy was admitted to Jikei University Hospital comp laining of gradual enlarging of the left scrotal contents. Methods/Results: Physical examination was significant for bilateral descend ed testicles. No abnormalities were detected in the testicles or along the spermatic cords. Scrotal ultrasound showed that hyperechoic shadows were re cognized in the central area of the left testicle. Subsequent testicular bi opsy and histopathological examination showed intratubular malignant germ c ells in the testicular tubules. One week later. left orchiectomy was perfor med. Conclusions: Histopathological evaluation revealed gonadoblastoma. Gonadobl astoma, a rare gonadal neoplasm, is composed of germ cells and sex cord der ivatives and usually occurs in phenotypically female patients with gonadal dysgenesis. To date, only three cases of gonadoblastoma have been reported in anatomically normal male patients with scrotal testicles. We report on a case of gonadoblastoma unaccompanied by a germ cell tumor in a physically normal male.