Identification of an insertion sequence, IS1203 variant, in a Shiga toxin 2 gene of Escherichia coli O157 : H7

Authors
Kusumoto, M Nishiya, Y Kawamura, Y Shinagawa, K
Citation
M. Kusumoto et al., Identification of an insertion sequence, IS1203 variant, in a Shiga toxin 2 gene of Escherichia coli O157 : H7, J BIOSCI BI, 87(1), 1999, pp. 93-96
Citations number
14
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
ISSN journal
13891723 → ACNP
Volume
87
Issue
1
Year of publication
1999
Pages
93 - 96
Database
ISI
SICI code
1389-1723(199901)87:1<93:IOAISI>2.0.ZU;2-E
Abstract
An insertion sequence composed of 1310 bp was found in Shiga toxin 2 genes of some isolates of Escherichia coil O157:H7. This insertion sequence showe d extremely high homology with IS1203 of E. coil O111:H-. This IS1203 varia nt was inserted in the region encoding the amino-terminus of the B subunit with a duplication of 3 bp at the target site, resulting in inactivation of the Shiga toxin 2 gene.