Lithium perchlorate mediated three component reaction for the preparation of primary amines

Citation
Mr. Saidi et al., Lithium perchlorate mediated three component reaction for the preparation of primary amines, J CHEM R-S, (5), 1999, pp. 330-331
Citations number
16
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF CHEMICAL RESEARCH-S
ISSN journal
03082342 → ACNP
Issue
5
Year of publication
1999
Pages
330 - 331
Database
ISI
SICI code
0308-2342(199905):5<330:LPMTCR>2.0.ZU;2-M
Abstract
In the presence of lithium perchlorate in diethyl ether, LPDE, a three-comp onent reaction between aldehydes, sodium hexamethyldisilazane or lithium he xamethyldisilazane, LHMDS, and different nucleophiles proceeds smoothly to afford primary amines in good yields.