Bacteremia may occur after disruption of the oral mucous membrane. particul
arly after dental treatment. 18 mentally handicapped patients who underwent
dental treatment with general anesthesia were included in our study. None
of the patients had general illnesses or received antibiotic protection. Fr
om each patient several blood samples were drawn aseptically during dental
treatment and cultured. The majority of aerobic bacteria recovered belonged
to Streptococcus sp and Gemella sp., anaerobic bacteria mainly belonged to
Porphyromonas gingivalis and Peptostreptococcus sp. Resistance of the isol
ated bacteria to penicillin as well as to oxacillin, erythromycin and Co-tr
imoxazole was substantial. The highest resistance rate could be shown again
st fucidic acid.