Trifluoromethylthiolation of aromatic substrates using thiophosgene-fluoride salt reagents, and formation of byproducts with multi-carbon chains

Authors
Tavener, SJ Adams, DJ Clark, JH
Citation
Sj. Tavener et al., Trifluoromethylthiolation of aromatic substrates using thiophosgene-fluoride salt reagents, and formation of byproducts with multi-carbon chains, J FLUORINE, 95(1-2), 1999, pp. 171-176
Citations number
20
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
JOURNAL OF FLUORINE CHEMISTRY
ISSN journal
00221139 → ACNP
Volume
95
Issue
1-2
Year of publication
1999
Pages
171 - 176
Database
ISI
SICI code
0022-1139(19990604)95:1-2<171:TOASUT>2.0.ZU;2-I
Abstract
Reaction of potassium fluoride or tetramethylammonium fluoride with thiopho sgene leads to the formation of a nucleophilic source of trifluoromethaneth iolate, suitable for the preparation of trifluoromethyl aryl sulfides from activated haloaromatics. Analysis of the byproducts in the system demonstra tes that complex molecules with up to C-4 chains may be formed by the react ion of fluoride salts with thiophosgene. (C) 1999 Elsevier Science S.A. All rights reserved.