Spontaneous intralesional haemorrhage in dysembryoplastic neuroepithelial rumours: a series of five cases

Citation
M. Thom et al., Spontaneous intralesional haemorrhage in dysembryoplastic neuroepithelial rumours: a series of five cases, J NE NE PSY, 67(1), 1999, pp. 97-101
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
ISSN journal
00223050 → ACNP
Volume
67
Issue
1
Year of publication
1999
Pages
97 - 101
Database
ISI
SICI code
0022-3050(199907)67:1<97:SIHIDN>2.0.ZU;2-Q
Abstract
Five patients with dysembryoplastic neuroepithelial tumour (DNT) showing ex tensive secondary haemorrhage, a finding not previously associated with the se neoplasms, are described. The clinical presentations, neuroimaging findi ngs, and histopathological features of these patients are reviewed. One pat ient, a previously asymptomatic 12 year old girl, presented with an acute i ntracerebral haemorrhage into a DNT. A further four young adults with histo ries of intractable partial and generalised seizures dating from childhood showed significant chronic haemorrhages within DNT, the MRI appearances in one patient giving a false impression of a cavernoma. Histopathology disclo sed vascular abnormalities within these tumours which, together with other factors discussed, may have predisposed these tumours to haemorrhage.