M. Thom et al., Spontaneous intralesional haemorrhage in dysembryoplastic neuroepithelial rumours: a series of five cases, J NE NE PSY, 67(1), 1999, pp. 97-101
Five patients with dysembryoplastic neuroepithelial tumour (DNT) showing ex
tensive secondary haemorrhage, a finding not previously associated with the
se neoplasms, are described. The clinical presentations, neuroimaging findi
ngs, and histopathological features of these patients are reviewed. One pat
ient, a previously asymptomatic 12 year old girl, presented with an acute i
ntracerebral haemorrhage into a DNT. A further four young adults with histo
ries of intractable partial and generalised seizures dating from childhood
showed significant chronic haemorrhages within DNT, the MRI appearances in
one patient giving a false impression of a cavernoma. Histopathology disclo
sed vascular abnormalities within these tumours which, together with other
factors discussed, may have predisposed these tumours to haemorrhage.