To assess the clinical efficacy of a pelvic floor rehabilitation (PFR) prog
ram for treatment of genuine stress incontinence (GSI), we studied 72 patie
nts with slight to moderate (2-10 g of urine loss per hour) or severe (11-5
0 g of urine loss per hour) GSI who underwent PFR. Objective and subjective
assessments were performed before and 3, 6, 12, 18, and 24 months after th
e start of treatment. The overall success rate (complete cure or marked imp
rovement in symptoms) was 61% (44/72) at the S-year follow-up. The number o
f leakages per 24 hours and urine loss in the 1-hour pad test were signific
antly reduced, and vaginal muscle strength was significantly increased in s
uccessfully-treated patients. Significant changes were also observed in sym
ptoms of micturition frequency and nocturia and in volume at first desire t
o void during cystometry in the treatment success group. Patient compliance
with the exercise program was a significant predictor of success. The succ
ess rate during the 2-year follow-up period, estimated according to patient
compliance, also differed significantly among groups, with good, moderate,
and poor compliance. Patients experienced no serious adverse effects. Thes
e results show that the PFR program used in this study is an effective alte
rnative to surgical intervention for the treatment of GSI in selected patie
nts.