Interpretation of high levels of HIV-1 RNA in the cerebrospinal fluid (CSP) using amplicor HIV-D monitor test

Citation
P. Honderlick et al., Interpretation of high levels of HIV-1 RNA in the cerebrospinal fluid (CSP) using amplicor HIV-D monitor test, PATH BIOL, 47(5), 1999, pp. 560-562
Citations number
6
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
PATHOLOGIE BIOLOGIE
ISSN journal
03698114 → ACNP
Volume
47
Issue
5
Year of publication
1999
Pages
560 - 562
Database
ISI
SICI code
0369-8114(199905)47:5<560:IOHLOH>2.0.ZU;2-R
Abstract
A retrospective study of 19 cerebrospinal fluid (CSF) specimens from 14 HIV -positive subjects with subacute encephalopathy, neuropathy, or unexplained peripheral myelopathy was done comparatively with plasma specimens collect ed on the same day and tested in the same run as the corresponding CSF spec imen. A single patient had a high HIV RNA level in CSF as compared to plasm a (CSF/plasma ratio > 10), which seemed correlated with the clinical course . Further studies are needed to confirm that a high CSF/plasma HIV RNA rati o is associated with greater symptom severity.