Biotransformation of the diperpenoid, isosteviol, by Aspergillus niger, Penicillium chrysogenum and Rhizopus arrhizus

Authors
de Oliveira, BH dos Santos, MC Leal, PC
Citation
Bh. De Oliveira et al., Biotransformation of the diperpenoid, isosteviol, by Aspergillus niger, Penicillium chrysogenum and Rhizopus arrhizus, PHYTOCHEM, 51(6), 1999, pp. 737-741
Citations number
12
Categorie Soggetti
Agricultural Chemistry","Animal & Plant Sciences
Journal title
PHYTOCHEMISTRY
ISSN journal
00319422 → ACNP
Volume
51
Issue
6
Year of publication
1999
Pages
737 - 741
Database
ISI
SICI code
0031-9422(199907)51:6<737:BOTDIB>2.0.ZU;2-L
Abstract
The biotransformation of isosteviol (ent-16-ketobeyeran-19-oic acid) by thr ee fungi is described. Aspergillus niger produced the 7 beta-OH derivative, ent-7 alpha-hydroxy-16-ketobeyeran-19-oic, and the 1 alpha,7 beta-diOH der ivative, ent-1 beta,7 alpha-dihydroxy-16-ketobeyeran-19-oic acid. The 17-OH compound, ent-17-hydroxy-16-ketobeyeran-19-oic acid, was obtained with Pen icillium chrysogenum. Rhizopus arrhizus produced the 7 beta-OH derivative, ent-7 alpha-hydroxy-16-ketobeyeran-19-oic acid. The isolated metabolites we re characterised by IR, NMR and MS. (C) 1999 Elsevier Science Ltd. All righ ts reserved.