Microbial transformation of parthenolide

Authors
Galal, AM Ibrahim, ARS Mossa, JS El-Feraly, FS
Citation
Am. Galal et al., Microbial transformation of parthenolide, PHYTOCHEM, 51(6), 1999, pp. 761-765
Citations number
21
Categorie Soggetti
Agricultural Chemistry","Animal & Plant Sciences
Journal title
PHYTOCHEMISTRY
ISSN journal
00319422 → ACNP
Volume
51
Issue
6
Year of publication
1999
Pages
761 - 765
Database
ISI
SICI code
0031-9422(199907)51:6<761:MTOP>2.0.ZU;2-C
Abstract
Microbial transformation of the germacranolide parthenolide using Rhizopus nigricans, Streptomyces fulvissimus and Rhodotorula rubra yielded three new compounds: 11 alpha H-dihydroparthenolide, 9 beta-hydroxy-11 beta H-dihydr oparthenolide and 14-hydroxy-11 beta H-dihydroparthenolide. 11 beta H-dihyd roparthenolide was the only common metabolite produced by all microorganism s. (C) 1999 Elsevier Science Ltd. All rights reserved.