Limonoids from fruit of Melia toosendan and their cytotoxic activity

Authors
Tada, K Takido, M Kitanaka, S
Citation
K. Tada et al., Limonoids from fruit of Melia toosendan and their cytotoxic activity, PHYTOCHEM, 51(6), 1999, pp. 787-791
Citations number
11
Categorie Soggetti
Agricultural Chemistry","Animal & Plant Sciences
Journal title
PHYTOCHEMISTRY
ISSN journal
00319422 → ACNP
Volume
51
Issue
6
Year of publication
1999
Pages
787 - 791
Database
ISI
SICI code
0031-9422(199907)51:6<787:LFFOMT>2.0.ZU;2-K
Abstract
Two new limonoids, toosendanal and 12-O-methylvolkensin, were isolated from the fruits of Melia toosendan Sieb. et Zucc. along with three known limono ids, meliatoxin B-1, trichilin H, and toosendanin. The structures of the ne w limonoids were established by spectroscopic methods, with toosendanal hav ing C-1/C-29 and C-19/C-29 acetal bridges. Both meliatoxin B-1 and toosenda nin exhibit cytotoxic activity against KB cells. (C) 1999 Elsevier Science Ltd. All rights reserved.