Two new derivatives of monoterpene alkaloids, named incarvillateine C and i
ncarvillateine D which are related to an antinociceptive alkaloid, incarvil
lateine, were isolated from the aerial parts of Incarvillea sinensis LAM. O
n the basis of both chemical and spectroscopic evidence, the structures of
the first two were characterized as a bis-demethoxy and demethoxy derivativ
es of incarvillateine, respectively. (C) 1999 Elsevier Science Ltd. All rig
hts reserved.