Correlation between biological activity and energies of electronic transitions in benzodiazepines. Negative ion mass spectrometry and ultraviolet absorption spectroscopy study of some derivatives
Og. Khvostenko et al., Correlation between biological activity and energies of electronic transitions in benzodiazepines. Negative ion mass spectrometry and ultraviolet absorption spectroscopy study of some derivatives, RAP C MASS, 13(12), 1999, pp. 1091-1097
A correlation between the energies of electronic singlet transitions in ben
zodiazepines and their biological activity, which was revealed earlier by m
eans of negative ion mass spectrometry with resonance electron capture, has
been verified with a UV absorption spectroscopy investigation. Also, it ha
s been noted that the energies of electronic singlet transitions in benzodi
azepines are close in value to the ionization energies of atoms Cs, ph, K,
Na, Li and Tl, the cations of which are known to play an important role in
nerve cell excitation processes. Copyright (C) 1999 John Wiley & Sons, Ltd.