Hot papers - Genetics - Positional cloning of the gene for multiple endocrine neoplasia-type I by S.C. Chandrasekharappa, S.C. Guru, P. Manickam, S. Olufemi, F.S. Collins, M.R. Emmert-Buck, L.V. Deblenko, Z. Zhuang, I.A. Lubensky, L.A. Liotta, J.S. Crabtree, Y. Wang, B.A. Roe, J. Weisemann, M. Boguski, S.K. Agarwal, M.B. Kester, Y.S. Kim, C. Heppener, Q. Dong, A.M. Spiegel, A.L. Burns, S.J. Marx - Comments

Francis S. Collins and Settara C. Chandrasekharappa of the National Human G enetics Research Institute and Allen M. Spiegel and Stephen J. Marx of the National Institute of Diabetes and Digestive and Kidney Diseases discuss th e search for MENI, a tumor suppressor gene.