Jd. Winkler et al., Design and synthesis of constrained epothilone analogs: The efficient synthesis of eleven-membered rings by olefin metathesis, TETRAHEDRON, 55(27), 1999, pp. 8199-8214
The efficient synthesis of both left- and right-hand halves of a constraine
d analog of the anticancer natural product epothilone is described. The ele
ven-membered rings common to both compounds are prepared by olefin metathes
is. (C) 1999 Elsevier Science Ltd. All rights reserved.