M. Schartl et al., STRESS ECHOCARDIOGRAPHY IN SPECIAL GROUPS - IN WOMEN, IN LEFT-BUNDLE-BRANCH BLOCK, IN HYPERTENSION AND AFTER HEART-TRANSPLANTATION, European heart journal, 18, 1997, pp. 63-67
The non-invasive diagnosis of coronary artery disease by exercise elec
trocardiography is less accurate in women than in men, with a high rat
e of false-positive results in women. In contrast, recent studies have
demonstrated that stress echocardiography in women is more accurate t
han exercise echocardiography and that the significantly higher specif
icity of stress electrocardiography may have the benefit of avoiding u
nnecessary angiography in women. Exercise-induced changes in the elect
rocardiogram are nondiagnostic in the presence of left bundle branch b
lock or basal ST changes. In these patients, stress echocardiography c
an be used instead of conventional scintigraphy for the detection of c
oronary artery disease, but further echocardiographic studies are need
ed to confirm the promising results. Exercise electrocardiography and
exercise echocardiography have been reported to be disappointing in th
e early detection of cardiac allograft vasculopathy after heart transp
lantation, and dobutamine stress echocardiography overestimates the in
cidence of angiographic evidence of cardiac allograft vasculopathy. Ho
wever, compared to intravascular ultrasound imaging, dobutamine stress
echocardiography seems to be a suitable non-invasive method for detec
ting cardiac allograft vasculopathy.