Citation
G. Anderluh et al., Equinatoxins, pore-forming proteins from the sea anemone Actinia equina, belong to a multigene family, TOXICON, 37(10), 1999, pp. 1391-1401
Citations number
22
Categorie Soggetti
Pharmacology & Toxicology
Journal title
TOXICON
ISSN journal
00410101
→ ACNP
Volume
37
Issue
10
Year of publication
1999
Pages
1391 - 1401
Database
ISI
SICI code
0041-0101(199910)37:10<1391:EPPFTS>2.0.ZU;2-#
Abstract
The multigene family of equinatoxins, pore-forming proteins from sea anemon
e Actinia equina, has been studied at the protein and gene levels. We repor
t the cDNA sequence of a new, sphingomyelin inhibited equinatoxin, EqtIV. T
he N-terminal sequences of natural Eqt I and III were also determined, conf
irming two isoforms of EqtI, differing at position 13, The number of Eqt ge
nes determined by Southern blot hybridization was found to be more than fiv
e, indicating that Eqts belong to a multigene family. (C) 1999 Elsevier Sci
ence Ltd. All rights reserved.