Squamous cell carcinoma and lipomatous pseudohypertrophy of the pancreas

A 68-year-old woman who had been treated for non-insulin-dependent diabetes mellitus for the past 20 years was admitted to hospital because of abdomin al pain and weight loss. Radiological investigation revealed a tumour in th e body of the pancreas and numerous intraductal calcifications in both the tail and the head of the pancreas. Left-sided pancreatectomy was performed to remove the tumour. The resection specimen showed fatty enlargement of th e parenchyma and numerous intraductal calcifications in the tissue adjacent to the tumour, which was 7 cm in diameter and was found to be a primary sq uamous cell carcinoma with a spindle cell component. There was also lipomat ous pseudohypertrophy.