Objectives. This study was conducted to define factors associated with the
epidemic spread, elimination, and reintroduction of primary and secondary s
yphilis in King County, Washington, from 1987 through 1998.
Methods. Reports of primary and secondary syphilis in King County from 1987
through 1998 were reviewed retrospectively.
Results. During the epidemic spread of syphilis, only 15.8% of cases were i
mported. A total of 24.0% of patients reported cocaine use, and 18.3% of fe
male patients reported having commercial sex. During the elimination of syp
hilis, significantly higher percentages of cases were imported and lower pe
rcentages of patients reported cocaine use or female commercial sex. During
the reintroduction of syphilis in 1997-1998, 68% of patients were men who
reported sex with men; of this 68%, 66% were seropositive for HIV Most men
reporting sex with men were 30 years or older and recruited many anonymous
partners.
Conclusions. As syphilis wanes, local control must focus on outbreaks follo
wing its reintroduction. Resurgence of syphilis among men reporting sex wit
h men recapitulates the epidemiology of syphilis before the historical adve
nt of AIDS, warranting immediate attention to this problem.