This paper addresses the development of new formulations for estimating mod
eling errors or unmeasured disturbances to be used in Model Predictive Cont
rol (MPC) algorithms during open-loop prediction. Two different formulation
s were developed in this paper. One is used in MPC that directly utilizes l
inear models and the other in MPC that utilizes non-linear models. These es
timation techniques were utilized to provide robust performance for MPC alg
orithms when the plant is open-loop unstable and under the influence of mod
eling error and/or unmeasured disturbances. For MPC that utilizes a non-lin
ear model, the estimation technique is formulated as a fixed small size on-
line optimization problem, while for linear MPC, the unmeasured disturbance
s are estimated via a proposed linear disturbance model. The disturbance mo
del coefficients are identified on-line from historical estimates of plant-
model mismatch. The effectiveness of incorporating these proposed estimatio
n techniques into MPC is tested through simulated implementation on non-lin
ear unstable exothermic fluidized bed reactor. Closed-loop simulations prov
ed the capability of the proposed estimation methods to stabilize and, ther
eby, improve the MPC performance in such cases.