Hypothesis: Laparoscopic techniques can be used to treat patients whose ant
ireflux surgery has failed.
Design: Case series.
Setting: Two academic medical centers.
Patients: Forty-six consecutive patients, of whom 21 were male and 25 were
female (mean age, 55.6 years; range, 15-80 years). Previous antireflux proc
edures were laparoscopic (21 patients), laparotomy (21 patients), thoracoto
my (3 patients), and thoracoscopy (1 patient).
Main Outcome Measures: The cause of failure, operative and postoperative mo
rbidity, and the level of follow-up satisfaction were determined for all pa
tients.
Results: The causes of failure were hiatal herniation (31 patients [67%]),
fundoplication breakdown (20 patients [43%]), fundoplication slippage (9 pa
tients [20%]), tight fundoplication (5 patients [11%]), misdiagnosed achala
sia (2 patients [4%]), and displaced Angelchik prosthesis (2 patients [4%])
. Twenty-two patients (48%) had more than 1 cause. Laparoscopic reoperative
procedures were Nissen fundoplication (n = 22), Toupet fundoplication (n =
13), paraesophageal hernia repair (n = 4), Dor procedure in = 2), Angelchi
k prosthesis removal (n = 2), Heller myotomy (n = 2), and the takedown of a
wrap (n = 1). In addition, 18 patients required crural repair and 13 requi
red paraesophageal hernia repair. The mean +/- SEM duration of surgery was
3.5 +/- 1.1 hours. Operative complications were fundus tear (n = 8), signif
icant bleeding in = 4), bougie perforation (n = 1), small bowel enterotomy
(n = 1), and tension pneumothorax (n = 1). The conversion rate (from laparo
scopic to an open procedure) was 20% overall (9 patients) but 0% in the las
t 10 patients. Mortality was 0%. The mean +/- SEM hospital stay was 2.3 +/-
0.9 days for operations completed laparoscopically. Follow-up was possible
in 35 patients (76%) at 17.2 +/- 11.8 months. The well-being score (1 best
; 10, worst) was 8.6 +/- 2.1 before and 2.9 +/- 2.4 after surgery (P < .001
). Thirty-one (89%) of 35 patients were satisfied with their decision to ha
ve reoperation.
Conclusions: Antireflux surgery failures are most commonly associated with
hiatal herniation, followed by the breakdown of the fundoplication. The lap
aroscopic approach may be used successfully to treat patients with failed a
ntireflux operations. Good results were achieved despite the technical diff
iculty of the procedures.