We observed the nearby starburst galaxy NGC 253 in the mid-infrared to obta
in a three-dimensional data set with arcsecond angular resolution and 0.2 m
u m spectral resolution. The observations show the major spectral features
in the upper half of the mid-IR window: the 11.3 mu m polycyclic aromatic h
ydrocarbon (PAH) line and the 12.8 mu m [Ne II] line as well as the broad s
ilicate absorption feature at 9.7 mu m. We use the [Ne II] line to determin
e the emission measure of the ionized gas, and in combination with radio ob
servations to predict the thermal and nonthermal contributions to the radio
continuum. The amount of ionized gas is related to the rate of star format
ion. Based on the mid-IR spectra, we identify three major components in the
nucleus of NGC 243: an AGN in the center of the galaxy, a super-star clust
er also seen in optical images, and a larger scale diffuse envelope compose
d of an older population of supernova remnants and lower mass stars.