As clinical decision making gets ever more complex, new analytical approach
es are being developed to help. Decision analysis is used to structure comp
lex decision problems in an uncertain environment by systematically linking
decision choices with expected outcomes. Such models can include the proba
bilities of outcomes, patient preferences and costs. These models can help
to advise about therapeutic avenues. This paper examines the nature of deci
sion analysis, and explores the pitfalls that arise in interpreting the fin
dings from published studies.