An aged male patient with autoimmune hepatitis complicated by hepatocellular carcinoma

An 82-year-old male patient was admitted for liver dysfunction, Laboratory test showed the following data; aspartate aminotransferase (AST) 79 IU/l, a lanine aminotransferase (ALT) 28 IU/l, total bilirubin (T, Bil) 0.9 U, zinc sulfate turbidity test (ZTT) 48.9 U, gamma-globulin 4.9 g/dl, immunoglobul in G (IgG) 5,046 mg/dl, anti-nuclear antibodiesx320, anti-mitochondrial ant ibodies (-), hepatitis B virus surface antigen (HBsAg) (-), HBcAb (-), anti -hepatitis C virus (anti-HCV) (-), hepatitis C virus (HCV-RNA) (-), anti-he patitis G virus (anti-HGV) (-), alpha-fetoprotein 306.8 ng/ml, carcinoembry onic antigen (CEA) 2.3 ng/ml, carbohydrate antigen (CA) 19-9 77.2 U/ml. Abd ominal ultrasonography and computed tomography showed a large mass occupyin g most of the right lobe and portal thrombosis in the liver. Liver biopsy r evealed cirrhosis with inactive hepatitis in the nontumorous lesion and wel l-differentiated hepatocellular carcinoma in the tumorous lesion. We report a rare case of an aged male patient with autoimmune hepatitis complicated by hepatocellular carcinoma.