N. Anzai et al., Roles of vasopressin and hypertonicity in basolateral Na/K/2Cl cotransporter expression in rat kidney inner medullary collecting duct cells, JPN J PHYSL, 49(2), 1999, pp. 201-206
The basolateral Na/K/2CI cotransporter mRNA (rNKCC1) increased when the cul
tured kidney inner medullary collecting duct (IMCD) cells of rats were expo
sed to vasopressin (10(-8) M) and/or hypertonicity (500 mOsm/kgH(2)O), Howe
ver, only hypertonicity was effective in increasing the expression of rNKCC
1 protein.