Chromatographic evaluation of radiation-immobilized poly(methyloctylsiloxane) on titanium-grafted silica

Silica was chemically modified by reaction with titanium tetrachloride to g ive a titanium-grafted silica (Si-Ti). Poly(methyloctylsiloxane) (PMOS) was sorbed into the pores of this support, which was then gamma-irradiated (80 -120 kGy) and extracted with dichloromethane. Chromatographic performance o f the stationary phase was evaluated in terms of the efficiency (plates/m), resolution (R-s), retention factor (k) and asymmetry (A(s)) of a standard mixture of solutes of different polarities. gamma-Irradiation increases the quantity of retained PMOS and the efficiency of the resulting columns. The se stationary phases. initially loaded with 50% PMOS following titanium-gra fting, retained 32+/-2% of the PMOS. (C) 1999 Elsevier Science B.V. All rig hts reserved.