Kt. Lee et al., Effects of structured lipid containing omega-3 and medium chain fatty acids on serum lipids and immunological, variables in mice, J FOOD BIOC, 23(2), 1999, pp. 197-208
Diets supplemented with enzymatically produced structured lipid (SL) contai
ning n-3 polyunsaturated fatty acids (eicosapentaenoic and docosahexaenoic)
and caprylic acid or soybean oil (16.7 g/100 g) were fed to 4 to 6 week ol
d female mice for 21 days. The effect of the diets on serum lipids (HDL-cho
lesterol, LDL-cholesterol, total cholesterol, triacylglycerol) and glucose
concentrations were determined. The concentration of total cholesterol (49%
), LDL cholesterol (35.4%) and triacylglycerol (53.2%) were significantly l
owered in SL-fed group. The body weight gain in mice fed the soybean oil di
et (control group) was significantly (p < 0.05) greater than that in mice f
ed the SL diet after 21 days. The proportion of total T-cells (Thy 1.2(+)),
T helper cells (CD4(+)), and T cytotoxic-suppressor cells (CD8(+)) in sple
en were not significantly different between the two dietary groups as deter
mined by flow cytometry.