J. Lambrechtsen et al., Tracking and factors predicting rising in 'tracking quartile' in blood pressure from childhood to adulthood: Odense Schoolchild Study, J HUM HYPER, 13(6), 1999, pp. 385-391
This prospective study determines the degree of tracking and investigates f
actors predicting a rise in blood pressure (BP) quartile in a cohort of 136
9 subjects who were followed for 11 years from childhood into young adultho
od. In 900 of these subjects BP, height, weight, physical fitness and BP re
sponses to a maximal exercise testing were measured both at baseline and at
follow-up. BP, weight, height and body mass index (BMI) were divided into
sex-specific quartiles at both examinations. Tracking was evaluated by exam
ining the tendency of remaining in the same quartile from baseline to follo
w-up and by measuring product-moment correlation coefficients. Tracking in
the upper and lower quartile for BP, weight, height and BMI were significan
t. Odds ratios for staying in the upper or lower quartile through the follo
w-up period ranged from 1.6 to 2.4 for diastolic BP and from 2.1 to 3.1 for
systolic BP. The range of correlation coefficients for the anthropometric
measurements were 0.57-0.75, for diastolic BP 0.12-0.22 and for systolic BP
0.34-0.36 respectively. Changes in weight or relative weight as well as BP
response to an exercise test were the factors which predicted a rise in qu
artile through the 11 years of followup. The existence of the inevitable re
gression to the mean problem in large longitudinal studies of BP was demons
trated by the finding of baseline BP being a significant factor in the pred
iction of rising in systolic, diastolic or both systolic and diastolic BP q
uartiles.