Background. Right radical neck dissection has been shown to prolong th
e QT interval, reportedly caused by surgical trauma to the cervical au
tonomic system, which may result in malignant ventricular arrhythmias.
Carotid artery resection would be expected to be more likely to cause
dangerous arrhythmias. Methods. We prospectively studied eight patien
ts with electrocardiograms before and after carotid resection. Four pa
tients had left-sided procedures and four patients had right-sided pro
cedures. In addition, 11 patients were studied retrospectively. QT int
ervals were normal in all patients preoperatively. Results. Preoperati
ve corrected QT intervals (QTc) were in the normal range used by our i
nstitution for all eight patients in the prospective group. There were
no significant QTc changes after either left-sided or right-sided car
otid resection. However, the retrospective group did show significant
changes in QTc following right carotid resection (n = 5), but not left
resection (n = 6). Conclusions. EKG changes associated with carotid r
esection may not be uniform and may depend on surgical technique or sp
ecific anatomic factors. Controlled prospective studies are needed to
confirm the prevalence of QT interval changes in radical neck surgery.
(C) 1995 John Wiley and Sons, Inc.