T. Hokama et al., Isolation of respiratory bacterial pathogens from the throats of healthy infants fed by different methods, J TROP PEDI, 45(3), 1999, pp. 173-176
Most bacterial infections are caused by organisms that have already coloniz
ed the host. Bacterial attachment to pharyngeal cells and proliferation may
be necessary to infect the lower respiratory tract or middle ear. We inves
tigated the incidence of pathogenic bacteria isolated from the throat of he
althy infants with different feeding methods. The protecting role of breast
milk is also discussed. The incidence of respiratory bacterial pathogens is
olated from the oropharynx of 113 normal infants with different feeding met
hods was investigated. Group A beta haemolytic Streptococcus, Streptococcus
pneumoniae, Haemophilus influenzae and Moraxella catarrhalis were selected
as respiratory bacterial pathogens. No respiratory bacterial pathogens wer
e detected in breastfed and mixed-fed infants. Haemophilus influenzae and M
oraxella catarrhalis were isolated from the oropharynx of formula-fed infan
ts. The incidence of respiratory bacterial pathogens did differ among infan
ts with different feeding methods. These results suggest that breastmilk ma
y inhibit the colonization by respiratory bacterial pathogens of the throat
of infants, by enhancing mucosal immunity against respiratory tract infect
ion.