Mutations of the cationic trypsinogen gene in patients with chronic pancreatitis

Authors
Creighton, J Lyall, R Wilson, DI Curtis, A Charnley, R
Citation
J. Creighton et al., Mutations of the cationic trypsinogen gene in patients with chronic pancreatitis, LANCET, 354(9172), 1999, pp. 42-43
Citations number
5
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
LANCET
ISSN journal
01406736 → ACNP
Volume
354
Issue
9172
Year of publication
1999
Pages
42 - 43
Database
ISI
SICI code
0140-6736(19990703)354:9172<42:MOTCTG>2.0.ZU;2-J
Abstract
Nine out of 48 (19%) patients referred to a pancreatic clinic with a presum ed diagnosis of idiopathic chronic pancreatitis have been shown to have mut ations in the cationic trypsinogen gene (PRSSI), consistent with a previous ly unsuspected diagnosis of hereditary pancreatitis.