Analysis of major repetitive DNA sequences in the dog (Canis familiaris) genome

A systematic screening and analysis of repeated DNA sequences from a dog ge nomic library composed of small DNA inserts enabled us to characterize abun dant canine repetitive DNA families. Four main families were identified: i) a group of highly repeated tRNA-derived short interspersed repetitive DNA elements (tRNA-SINEs); ii) another type of SINE-like element that was mainl y found inserted into long interspersed repetitive elements (LINEs); iii) L INEs of the L1 type, and iv) satellite or satellite-like DNA. Surprisingly, no SINEs derived from 7SL RNA were found in the dog genome. These data sho uld help in the analysis of canine DNA sequences and in the design of canin e genome mapping reagents.