Primary brain myxoma, an unusual tumor of meningeal origin: Case report

OBJECTIVE AND IMPORTANCE: Primary myxoma of the central nervous system is a n extremely rare tumor arising from cells of primitive mesenchymal origin. Only two cases of primary intracranial myxoma have been described previousl y. We report a patient with a primary myxoma originating from the right fro ntoparietal convexity dura, which we studied in detail with diagnostic imag ing and pathological analysis. CLINICAL PRESENTATION: A female adolescent presented to the emergency depar tment with a 3-day history of mild headache, abdominal pain, and intermitte nt left-sided focal motor seizures. Neurological examination was remarkable for left leg hyperreflexia and difficulty with tandem gait. Cranial comput ed tomography and magnetic resonance imaging demonstrated an inhomogeneousl y enhancing mass in the right frontoparietal region. INTERVENTION: A right frontoparietal craniotomy was performed. During surge ry, a tumor appearing similar to a typical convexity meningioma was complet ely removed along with the dural attachment. CONCLUSION: The patient had an uneventful recovery and returned to normal a ctivity. Primary intracranial myxoma should be distinguished from other men ingeal tumors and metastatic cardiac myxoma by appropriate pathological ana lysis and cardiac evaluation. A circumscribed myxoma completely excised wit h adequate dural margin carries a good prognosis for surgical cure.