We investigated the possible contribution of black grape ingestion on plasm
a antioxidant status and wished to elucidate whether black grape might play
a protective role against free radical-mediated pathologic processes or no
t. After fasting blood was obtained, each volunteer consumed a certain amou
nt of grape and, consecutive blood samples were taken at the 2nd and 4th ho
urs after first blood. Antioxidant potential (AOP) value was measured in th
e plasma, in which significantly increased values were observed at the 4th
compared with the basal value. bur results suggest that black grape strengt
hens plasma AOP as does red wine. This result also support the hypothesis t
hat the protective effect of red wine against cellular peroxidation reactio
ns and atherogenesis mainly arises from its flavonoid constituents rather t
han alcoholic content. It means that people may gain enhanced antioxidant d
efence against atherosclerosis by consuming black grape as well instead of
drinking red wine if they really drinks for this aim. (C) 1999 Elsevier Sci
ence Inc.