Diagnostic criteria and treatment modalities

Classification criteria: Several systems of classification criteria have be en developed for Sjogren's syndrome. These systems allow patient classifica tion but do not constitute diagnostic criteria. The most widely used is bas ed on the Fox criteria which are totally specific but have low sensitivity The European criteria have satisfactory sensitivity and specificity. In clinical practice: In all cases, the elements comprising the sicca syndr ome must be identified. A labial biopsy for histology of the accessory sali vary glands may be helpful. A less extensive search is sometimes sufficient a the aim is uniquely diagnostic. Treatment of Sjogren's syndrome: Symptomatic treatment of the sicca syndrom e with local procedures is aimed at reducing the functional disorder. The s ystemic route is used to treat the dysimmune component. As in most connecti ve tissue diseases, most patients can be stabilized, limiting the functiona l consequences of the disease, but cure remains-illusive.