Peripheral nerve involvement: Peripheral nerve involvement is better known
than central nervous system involvement. The dominant features are sensorom
otor polyneuropathies or pure sensorial polyneuropathies.
Central nervous system: The manifestations are polymorphous, generally pres
enting as encephalitis and/or focal or multifocal involvement of the spinal
cord.
Other localizations: Diffuse encephalic involvement is less common: acute a
septic meningitis, intellectual deterioration. Psychiatric manifestations a
re also frequently observed.
Therapeutic options: Response to corticosteroid therapy or immunosuppressor
therapy can be spectacular but is unpredictable.