Subfascial endoscopic perforator surgery (SEPS) is an important tool in the
treatment of advanced chronic venous disease. Some important anatomic and
technical points of SEPS are reviewed in this article. Major complications,
such as wound infection and breakdown, are uncommon after SEPS, in contras
t to the traditional open Litton procedure, which makes SEPS the chosen sur
gical treatment. The clinical and hemodynamic improvements are summarized.
The patients who seem to benefit most are those with primary valvular insuf
ficiency as their underlying pathophysiology.