Retroperitoneoscopy has gained popularity because it offers a safe alternat
ive to the more debilitating open approach and avoids postoperative ileus.
However, this type of procedure carries certain disadvantages in terms of i
ntraperitoneal effusions and hemodynamic changes. Major complications are e
xceptional. We describe the case of a 52-year-old man who died of carbon di
oxide embolism during elective totally extraperitoneal (TEP) inguinal herni
oplasty for symptomatic left indirect inguinal hernia. With the patient und
er general anesthesia, the retroperitoneal space was gained through a 1.5-c
m incision made below the umbilicus. During the dissection, the patient col
lapsed and could not be resuscitated, At autopsy, air bubbles were admixed
with blood in the epicardial veins, but no injury to vessels was demonstrat
ed. We conclude that carbon dioxide embolism usually is caused by direct pu
ncture of major vessels during intra-abdominal procedures. However, when th
is complication occurs during retroperitoneoscopy, it seems related to pres
sure-forced entry of carbon dioxide into the venous plexus.