Intrasphincteric botulinum toxin type A for the diagnosis of sphincter of Oddi dysfunction: A case report

Biliary-type pain from sphincter of Oddi dysfunction is not uncommon after cholecystectomy. An increased basal pressure of sphincter of Oddi manometry establishes the diagnosis and treatment is usually by endoscopic sphincter otomy. Both procedures carry a significantcomplication rate a few patients with elevated sphincter pressure do not respond to therapy; the source of t heir pain may be elsewhere. This case report describes the use of intrasphi ncteric botulinum toxin injection for the diagnosis of sphincter of Oddi dy sfunction in a patient after repeated attempts at manometry had failed. Thi s may provide a safe and easy method of determining whether sphincter of Od di dysfunction may be the cause of biliary pain in post/cholecystectomy pat ients and help select patients who would benefit from subsequent sphincter ablation, without the risks of sphincter of Oddi manometry, Prospective stu dies are first needed.